Search results for "Atpase activity"

showing 6 items of 6 documents

Inhibition of Gill Na+,K+-ATPase Activity in the Eel,Anguilla anguilla,by Fenitrothion

1998

European eels (Anguilla anguilla) were exposed to sublethal fenitrothion concentrations (0.02 and 0.04 mg/liter) in a continuous flow-through system for 4 days. Gill Mg2+- and Na+,K+-ATPase activities were evaluated after 2, 8, 12, 24, 32, 48, 56, 72, and 96 h of pesticide exposure. Results indicated that ATPase activity in gill tissue decreased as concentration of fenitrothion increased. Pesticide induced significant inhibitory effects on the Na+, K+-ATPase activity of A. anguilla, ranging from >56% inhibition at a sublethal concentration of 0.02 ppm to >73% inhibition at a sublethal concentration of 0.04 ppm. Eels were exposed to both fenitrothion concentrations for 96 h and then allowed …

GillsInsecticidesanimal structuresHealth Toxicology and MutagenesisATPaseFenitrothionchemistry.chemical_compoundAnimal scienceAnguillidaeAnimalsNa k atpase activitychemistry.chemical_classificationDose-Response Relationship DrugbiologyPublic Health Environmental and Occupational HealthFenitrothionGeneral MedicineAnatomyPesticideAnguillabiology.organism_classificationPollutionDose–response relationshipEnzymechemistryToxicitybiology.proteinEnvironmental PollutantsSodium-Potassium-Exchanging ATPaseEcotoxicology and Environmental Safety
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Hemmung der Adenosintriphosphatase durch Colchicin

1951

The ATPase activity is inhibited by Colchicin in concentrations of 10−3 m and 10−4 m at a rate of 40 to 20 %, but in no way in the range of 10−7 m and 10−8 m, where Colchicin exerts its typical spindle-blocking action on the mitotic cell division. It is therefore no evidence, that Colchicin acts by influence on the energy yielding ATP-ATPase system, which was proposed to be responsible for the spindle contraction.

PharmacologyCellular and Molecular NeuroscienceContraction (grammar)PhosphataseMolecular MedicineAtpase activityCell BiologyBiologyMolecular BiologyMitosisMolecular biologyCell biologyExperientia
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Influence of Rhein on Rat Colonic Na<sup>+</sup>, K<sup>+</sup>-ATPase and Permeability in vitro

1988

Rhein, an aglucone of a laxative-acting anthraquinone, which induces net secretion in the human jejunum and colon, does not induce net secretion under open circuit current in in vitro conditions but r

PharmacologyGeneral MedicineAbsorption (skin)AnthraquinoneMolecular biologyIn vitroJejunumchemistry.chemical_compoundmedicine.anatomical_structureBiochemistrychemistryPermeability (electromagnetism)medicineAtpase activitySecretionNa+/K+-ATPasePharmacology
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Untersuchungen über den Einfluss verschiedener Kationen auf die ATP-Spaltung durch die Zytoplasmafraktion vom Plexus chorioideus des Rindes

1967

The cytoplasma fraction of the bovine choroid plexus epithelial cells was found to contain a considerable ATPase activity. The influence of Na+, K+, Li+, Rb+, Cs+, Co++, Mn++, Zn++ and Fe+++ on the activity of the Mg++-dependent enzyme has been studied. The monovalent cations do not influence the enzymic activity, whereas the effect of the bi- and trivalent cations is characterized by an inhibition of the ATPase.

Pharmacologychemistry.chemical_classificationPlexusbiologyATPaseCell BiologyCleavage (embryo)Medicinal chemistryMonovalent CationsCellular and Molecular NeuroscienceEnzymechemistryBiochemistryCytoplasmbiology.proteinMolecular MedicineAtpase activityChoroid plexusMolecular BiologyExperientia
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Evidence for essential primary amino groups in a bacterial coupling factor F1ATPase.

1980

Abstract We have found that the binding of pyridoxal-5′-phosphate to 6 primary amino groups leads to the inactivation of the enzyme. A preferential reaction of pyridoxal-5′-phosphate with the α-subunits of this enzyme can be demonstrated. The reactivity of the amino groups is influenced by various effectors. In the presence of ATP the inhibition of the ATPase activity is noncompetitive.

chemistry.chemical_classificationAdenosine TriphosphatasesPrimary (chemistry)Binding SitesChemistryStereochemistryEffectorCell MembraneBiophysicsCell BiologyBiochemistryMicrococcusCoupling (electronics)Structure-Activity RelationshipEnzymeBiochemistrySolubilityPyridoxal PhosphateAtpase activityReactivity (chemistry)Amino AcidsMolecular BiologyBiochemical and biophysical research communications
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Focal elevation of liver microsomal epoxide hydrolase in early preneoplastic stages and its behaviour in the further course of hepatocarcinogenesis.

1981

Abstract Treatment of rats with N-nitrosomorpholine (NNM) for 7 weeks led to a focal increase in liver microsomal epoxide hydrolase (EH) as early as 2 weeks after withdrawal of the carcinogen. This treatment also leads to hyperplastic nodules and liver tumors, but much later. At the same early time point, ATPase activity was decreased in the same islands. Most of these areas already had increased γ-glutamyltranspeptidase activity. The increase in EH at this early time point was more distinct than the decrease in ATPase which has thus far been considered a suitable marker of the earliest stages in hepatocarcinogenesis. The focal increase in EH was also observed in all benign hepatomas, but n…

medicine.medical_specialtyNitrosaminesATPaseBiophysicsBiochemistryLiver Neoplasms ExperimentalInternal medicinemedicineAtpase activityAnimalsMolecular BiologyCarcinogenAdenosine TriphosphatasesEpoxide HydrolasesbiologyLiver NeoplasmsCell Biologygamma-GlutamyltransferaseRatsEndocrinologyLiverMicrosomal epoxide hydrolasebiology.proteinMicrosomes LiverFemaleRabbitsHyperplastic nodulesPrecancerous ConditionsBiochemical and biophysical research communications
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